Another possibility is the use of DNA probe technology.
This utilises the tendency of two complementary singlestranded
DNA molecules to anneal together to produce a
double-stranded duplex. This method involves the DNA under
investigation being immobilised onto a solid support such as
nylon. A labelled single-stranded DNA probe may then be used
to determine whether a specific sequence is present. This
technique is often referred to as forward dot-blotting.
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